Cutaneous T-Cell Lymphoma
About Cutaneous T-Cell Lymphoma
One of the most common forms of T-cell lymphoma is cutaneous T-cell lymphoma (CTCL), a general term for T-cell lymphomas that involve the skin. CTCL can also involve the blood, lymph nodes, and other internal organs.
Symptoms can include dry skin, itching (which can be severe), a red rash, and enlarged lymph nodes. The disease affects men more often than women and usually occurs in men in their 40s, 50s, and 60s.
Most patients with CTCL experience only skin symptoms. Some patients with early stage CTCL might not progress to later stages at all, while others might progress rapidly with the cancer spreading to lymph nodes and/or internal organs.
Subtypes of CTCL
CTCL describes many different disorders with various symptoms, outcomes, and treatment considerations:
- Mycosis Fungoides (MF): the most common type of CTCL, accounting for approximately one-half of all CTCLs. MF can look different in each patient, with skin symptoms that can appear as patches, plaques, or tumors.
- Sézary Syndrome: characterized by the presence of lymphoma cells in the blood, patients with Sézary Syndrome often present with extensive thin, red, itchy rashes that typically appear on the skin.
Learn More
To learn more about CTCL, download the Cutaneous Lymphoma Fact Sheet. Want to talk to someone? For answers to lymphoma-related questions and resources, contact our Helpline at (800) 500-9976 or helpline@lymphoma.org.
Additional Resources
To learn more about CTCL, download the Cutaneous Lymphoma Fact Sheet.
Events

Ask the Doctor About Lymphoma: Information for Newly Diagnosed Patients
Ask the Doctor About Lymphoma is a virtual two-hour program that combines a comprehensive and […]

Drug Development and Clinical Trials for Lymphoma and CLL/SLL Webinar
Webinars are hour-long interactive programs discussing the diagnosis and treatment of specific lymphoma subtypes and […]

2025 Educational Forum on Lymphoma
The Educational Forum on Lymphoma is a virtual two-day conference in the fall of every year that […]