Researcher Spotlight: Reid Merryman, MD, MS Dana-FArber Cancer Institute Classical Hodgkin lymphoma (cHL) tumor cells have developed several ways to avoid detection and destruction by the immune system, including expression of immune checkpoint proteins on their surface to shield them…
Researcher Spotlight: Natalie Grover, MD The University of North Carolina at Chapel Hill Although a majority of patients with Hodgkin lymphoma (HL) are cured with first-line therapy; about 15 percent of those patients experience primary refractory disease or relapse after…
Researcher Spotlight: Yong Gu Lee, PhD The Trustees of the University of Pennsylvania Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma (NHL) and is the most common hematologic malignancy in the US. The prognosis…
Researcher Spotlight: Laurianne Scourzic, PhD Joan & Sanford I. Weill Medical College of Cornell University Many B-cell lymphoma patients are resistant to, or relapse after, treatment. While researchers have demonstrated the causal role of cancer stem cells in the relapsing…
Researcher Spotlight: Paolo Strati, MD University of Texas M.D. Anderson Cancer Center Patients with relapsed or refractory large B-cell lymphoma (LBCL) treated with chimeric antigen receptor (CAR) T cells have increased their cure rate from 10 percent to 40 percent.…
Researcher Spotlight: Abi Vijenthira, MD University Health Network Lymphoma is the most common blood cancer in Canada, and diffuse large B-cell lymphoma (DLBCL) has the greatest incidence in older patients compared to all other lymphomas. Older patients are at risk…
Researcher Spotlight: Christopher Strouse, MD The University of Iowa Follicular lymphoma (FL) is typically an indolent, or slow-growing, form of non-Hodgkin lymphoma accounts for 20 to 30 percent of all cases on non-Hodgkin lymphoma. Patients diagnosed with FL can typically…
Researcher Spotlight: Raphael Eric Steiner, MD University of Texas MD Anderson Cancer Center Primary mediastinal large B-cell lymphoma (PMLBCL), a type of diffuselarge B-cell lymphoma (DLBCL), affects predominantly adolescents and young adults and is usually treated with chemo-immune therapy with…
Researcher Spotlight: Christina Lee, MD Memorial Sloan Kettering Cancer Center It has become increasingly apparent that normal immune cells are important in disease progression and therapy resistance in lymphoma. Studies from a clinical trial of two targeted therapies, ibrutinib (Imbruvica)…
Researcher Spotlight: Boyu Hu, MD University of Utah/Huntsman Cancer Institute Gene mutations and chromosomal alterations found in relapsed/refractorychronic lymphocytic leukemia (CLL) makes the disease more resistant to currently approved therapies and prone to earlier relapses. While these gene changes are…
