Researcher Spotlight: Edward Dominguez, PhD BECKMAN RESEARCH INSTITUTE OF CITY OF HOPE HEALTH EQUITY INITIATIVE Cyclin-dependent kinases, including CDK9, are responsible for regulation of a variety of cellular processes that contribute to the growth and expansion of cancer cells. Using…
Researcher Spotlight: Ajlan Al Zaki, MD, PhD UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER Chimeric antigen receptor (CAR) T-cell therapies represent a meaningful treatment option for lymphoma, but many patients who receive these therapies will experience side effects caused by…
Researcher Spotlight: Christopher Sauter, MD Perelman School of Medicine, University of Pennsylvania Chimeric antigen receptor (CAR) T-cell therapies work by harnessing the power of T cells to kill lymphoma cells through a variety of cytotoxic mechanisms that are coordinated simultaneously.…
Researcher Spotlight: Yifei Liao, PhD BRIGHAM AND WOMEN’S HOSPITAL Several types of lymphomas have been associated with Epstein-Barr virus (EBV) infection. Little is known about how EBV manipulates cellular processes in lymphoma, though, including how it evades detection by the…
Researcher Spotlight: Anouchka Laurent, PhD Columbia University in the City of New York Understanding the mechanisms and molecules involved in the formation of T-cell lymphomas (TCL) can illuminate new potential targets for drug development. Dr. Laurent’s research is focused on…
Researcher Spotlight: Sanket Shah, PhD WEILL MEDICAL COLLEGE OF CORNELL UNIVERSITY DR. BRUCE D. CHESON FELLOW Diffuse large B-cell lymphomas (DLBCL) are a heterogeneous group of lymphomas associated with poor outcomes and high rates of mortality. Mutations in genes that…
Researcher Spotlight: Tayla Heavican-Foral, PhD DANA-FARBER CANCER INSTITUTE DR. OLIVER PRESS MEMORIAL FELLOW HEALTH EQUITY INITIATIVE Despite treatment advances in the lymphoma space, many patients with T-cell lymphomas (TCL) still experience limited response rates, often lasting for short durations, with…
Researcher Spotlight: Patrizia Mondello, MD, PhD MAYO CLINIC, ROCHESTER In most cases, follicular lymphoma (FL) is a slow-growing cancer associated with favorable outcomes. Some patients experience a more aggressive disease course, though, characterized by early relapse and poor outcomes. Crosstalk…
Researcher Spotlight: Elise Chong, MD University of Pennsylvania Perelman School of Medicine Health Equity Initiative Chimeric antigen receptor (CAR) T-cell therapy has become a life-saving treatment option for many people with large B-cell lymphoma. Some patients do not respond to…
Researcher Spotlight: Xiaolong (Alan) Zhou, MD NORTHWESTERN UNIVERSITY FEINBERG SCHOOL OF MEDICINE The abscopal effect refers to the infrequent ability of radiation therapy (RT) to stimulate antitumor immune responses that result in the shrinkage of tumors outside of RT-targeted sites.…