Research News

Trusting the Process and Celebrating Triumphs

Trusting the Process and Celebrating Triumphs Growing up in Cleveland, Ohio, Steven M. Horwitz, MD, a Medical Oncologist at Memorial Sloan Kettering Cancer Center, member of LRF’s Scientific Advisory Board, and co-chair of LRF’s Lymphoma Scientific Research Mentoring Program (LSRMP),…

Curiosity in Pursuit of a Cure

LRF grantee Abner Louissaint, MD, PhD has been interested in studying things since he was a child. His inquisitiveness followed him through his adult years and was a catalyst for his desire to pursue a career in the study of lymphoma.

A Pioneering Spirit

Dr. Eduardo Sotomayor is embarking on a new and exciting challenge in his career that will combine his pioneering work in cancer immunology and dedication to providing quality cancer care for all patients.

ASH 2021: Pivotal Data on CAR T Cell Therapy and Emerging Construct Presented at ASH

Investigation into the use of chimeric antigen receptor (CAR) T cell therapies has expanded rapidly in recent years, including for hematologic malignancies. Results from several key studies were presented at the 2021 Annual ASH Meeting, which demonstrated the use of these emerging therapies in multiple lines of therapy, new disease states, and using novel constructs to enhance responses.

ASH 2021: Polatuzumab Vedotin Reduces Risk for Disease Progression in Previously Untreated Diffuse Large B-Cell Lymphoma

In the phase III POLARIX study, a team of investigators led by LRF Scientific Advisory Board (SAB) member Christopher R. Flowers, MD, MSc of the University of Texas MD Anderson Cancer Center compared the efficacy of standard R-CHOP with that of a modified drug regimen, in which vincristine was replaced with the antibody-drug conjugate polatuzumab vedotin (pola-R-CHP).