Researcher Spotlight: Tayla Foral, PhD DANA-FARBER CANCER INSTITUTE Mature T-cell lymphomas (TCL) are a highlyheterogeneous group of diseases with poor treatment options. Currently, many patients with TCL experience relapsed or refractory disease, and outcomes are generally poor. Dr. Foral’s LRF…
Researcher Spotlight: Paola Ghione, MD MEMORIAL SLOAN KETTERING CANCER CENTER Lymphomas are a highly heterogeneous set of diseases, and while many people will do well with treatment, there are subsets of patients whose cancer does not respond or relapses quickly…
Researcher Spotlight: Niloufer Khan, MD, MS Memorial Sloan Kettering Cancer Center Cutaneous T-cell lymphoma (CTCL) is a type of skin lymphoma usually managed as a chronic disease without a standard frontline therapy, and treatment plans typically vary from patient to patient.…
Researcher Spotlight: Coraline Mlynarczyk, PhD Joan & Sanford I. Weill Medical College of Cornell University Diffuse Large B Cell Lymphoma (DLBCL) is a heterogenous B-cell malignancy, with each patient presenting with a heavy and diverse burden of alterations in their DNA. Therefore,…
Researcher Spotlight: Zachary Epstein-Peterson, MD Memorial Sloan Kettering Cancer Center In recent years, several new therapies have been investigated for treating T-cell lymphomas. Some of thesemedicines work in up to 50 percent of patients whoselymphoma has relapsed or has not responded to…
Researcher Spotlight: Luis Malpica Castillo, MD The University of Texas M.D. Anderson Cancer Center Adult T-cell leukemia/lymphoma (ATLL) is an aggressive, generally incurable type of non-Hodgkin lymphoma (NHL) caused by infection with the human T-cell leukemia virustype 1 (HTLV-1). This…
Researcher Spotlight: Edmond Feris, PhD Dartmouth-Hitchcock Norris Cotton Cancer Center Some of the most critical oncogenes responsible fortumor formation in humans are transcription factors. Dr.Feris’ LRF research project focuses on the study of howtranscriptional dysregulation can lead to carcinogenesis(the process…
Researcher Spotlight: Marco Ruella, MD Perelman School of Medicine, University of Pennsylvania Chimeric antigen receptor (CAR) T cell therapy has been very successful in certain cancers, such as B-cell leukemia and lymphoma. However, the needle has not moved for most…
Researcher Spotlight: Owen A. O’Connor, MD, PhD Columbia University Medical Center A long-time member of the Lymphoma Research Foundation’s Scientific Advisory Board , and a founding Executive Committee member of LRF’s Mantle Cell Lymphoma Consortium, Dr. Owen O’Connor has been…